4TU9
STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Splicing factor U2AF 65 kDa subunit | polymer | 174 | 19075.8 | 2 | UniProt (P26368) Pfam (PF00076) | Homo sapiens (Human) | U2 auxiliary factor 65 kDa subunit,hU2AF65,U2 snRNP auxiliary factor large subunit |
| 2 | C, D (P, E) | DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DG*U)-3') | polymer | 7 | 2104.1 | 2 | Homo sapiens | ||
| 3 | E, F, G, L, M (A, B) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 5 | Chemie (DIO) | |||
| 4 | H, I, J, O, P... (A, B) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | K, R (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 6 | N (B) | N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE | non-polymer | 862.1 | 1 | Chemie (CPQ) PubChem (3609263) PubChem (44658112) PubChem (45933557) PubChem (46936249) PubChem (16402218) PubChem (446320) PubChem (75361254) PubChem (90277687) PubChem (102565423) PubChem (124867695) PubChem (124905380) PubChem (124905378) PubChem (124919192) PubChem (124933353) PubChem (124933355) PubChem (125027417) PubChem (129891641) PubChem (132470929) PubChem (135639079) PubChem (139981181) PubChem (71299811) PubChem (122130317) PubChem (124837856) PubChem (124905379) PubChem (124905381) PubChem (124919193) PubChem (124919194) PubChem (124919195) PubChem (124933354) PubChem (124933356) PubChem (171036883) | |||
| 7 | S, T, U, V (A, B, P, E) | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A, B: 148 - 336 (UniProt: P26368)
| PDB | External Database | Details |
|---|---|---|
| Gly 143 | - | expression tag |
| Pro 144 | - | expression tag |
| Leu 145 | - | expression tag |
| Gly 146 | - | expression tag |
| Ser 147 | - | expression tag |
| - | Met 238 | deletion |
| - | Ser 239 | deletion |
| - | Glu 240 | deletion |
| - | Asn 241 | deletion |
| - | Pro 242 | deletion |
| - | Ser 243 | deletion |
| - | Val 244 | deletion |
| - | Tyr 245 | deletion |
| - | Val 246 | deletion |
| - | Pro 247 | deletion |
| - | Gly 248 | deletion |
| - | Val 249 | deletion |
| - | Val 250 | deletion |
| - | Ser 251 | deletion |
| - | Thr 252 | deletion |
| - | Val 253 | deletion |
| - | Val 254 | deletion |
| - | Pro 255 | deletion |
| - | Asp 256 | deletion |
| - | Ser 257 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 42359.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2063.1 | |
| All* | Total formula weight | 44422.9 |
