4TMA
Crystal structure of gyrase bound to its inhibitor YacG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | DNA gyrase subunit A | polymer | 525 | 58955.4 | 4 | UniProt (U6NB78) | Escherichia coli | |
| 2 | B, D, F, H (B, D, F, H) | DNA gyrase subunit B | polymer | 417 | 47338.6 | 4 | UniProt (U6NGU8) | Escherichia coli | |
| 3 | I, J, K, L (I, J, K, L) | DNA gyrase inhibitor YacG | polymer | 65 | 7313.1 | 4 | UniProt (P0A8H8) Pfam (PF03884) | Escherichia coli | |
| 4 | M, N, O, P, Q... (B, E, I, J, K...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) |
Sequence modifications
B, D, F, H: 388 - 801 (UniProt: U6NGU8)
| PDB | External Database | Details |
|---|---|---|
| Ser 385 | - | expression tag |
| Asn 386 | - | expression tag |
| Ala 387 | - | expression tag |
| Tyr 458 | Phe 458 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 454428.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 454821.1 |
