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4S0O

Crystal Structure of the Autoinhibited Dimer of Pro-apoptotic BAX (I)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Apoptosis regulator BAXpolymer19221164.32UniProt (Q07812)
Pfam (PF00452)
Homo sapiens (human)Bcl-2-like protein 4, Bcl2-L-4
2C, D
(A, B)
waterwater18.0124Chemie (HOH)
Sequence modifications
A, B: 1 - 192 (UniProt: Q07812)
PDBExternal DatabaseDetails
Gly 168Pro 168engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42328.6
All*Total formula weight42328.6
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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