4RM5
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase NDM-1 | polymer | 242 | 25630.8 | 4 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | NDM-1, Metallo-beta-lactamase NDM-1 |
| 2 | E, F, G, H, I... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 588 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 29 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Asn 124 | Asp 124 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 102523.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 523.3 | |
| All* | Total formula weight | 103046.6 |
