4RHY

Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Hypoxanthine-guanine phosphoribosyltransferase	polymer	201	22140.9	4	UniProt (A5U8U8) Pfam (PF00156) UniProt (by SIFTS) (P9WHQ9)	Mycobacterium tuberculosis
2	E, F, H, I, K... (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
3	G, J, M, P (A, B, C, D)	[2-({2-[bis(2-phosphonoethyl)amino]ethyl}[2-(6-oxo-3,6-dihydro-9H-purin-9-yl)ethyl]amino)ethyl]phosphonic acid	non-polymer		546.3	4	Chemie (3QG)
4	Q, R, S, T (A, B, C, D)	water	water		18.0	237	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	88563.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2379.8
All*	Total formula weight	90943.5

*Water molecules are not included.