4RDQ
Calcium-activated chloride channel bestrophin-1, from chicken, in complex with Fab antibody fragments, chloride and calcium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Bestrophin-1 | polymer | 409 | 47614.3 | 5 | UniProt (E1C3A0) | Gallus gallus (bantam chickens) | Best1 |
| 2 | F, H, J, L, N (F, H, J, L, N) | Fab antibody fragment, light chain | polymer | 212 | 23339.7 | 5 | Mus musculus (mouse) | ||
| 3 | G, I, K, M, O (G, I, K, M, O) | Fab antibody fragment, heavy chain | polymer | 217 | 23638.5 | 5 | Mus musculus (mouse) | ||
| 4 | DA, LA, P, RA, W (C, D, A, E, B) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | AA, FA, GA, HA, NA... (B, C, D, A, E) | CHLORIDE ION | non-polymer | 35.5 | 15 | Chemie (CL) | |||
| 6 | EA, MA, S, SA, X (C, D, A, E, B) | CALCIUM ION | non-polymer | 40.1 | 5 | Chemie (CA) | |||
| 7 | BA, IA, JA, U, WA (B, C, A, E) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
| 8 | CA, KA, QA, V, XA (B, C, D, A, E) | 6-cyclohexyl-2-(4-cyclohexylbutyl)-2-({[4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}methyl)hexyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside | non-polymer | 1001.2 | 5 | Chemie (C6N) | |||
| 9 | AB, BB, CB, YA, ZA (C, D, E, A, B) | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 405 (UniProt: E1C3A0)
| PDB | External Database | Details |
|---|---|---|
| Glu 406 | - | expression tag |
| Gly 407 | - | expression tag |
| Glu 408 | - | expression tag |
| Glu 409 | - | expression tag |
| Phe 410 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 472962.9 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 6393.9 | |
| All* | Total formula weight | 479356.8 |
