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4R8Q

Structure and substrate recruitment of the human spindle checkpoint kinase bub1

Replaces:  3E7E
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitotic checkpoint serine/threonine-protein kinase BUB1polymer36541847.61UniProt (O43683)
Pfam (PF00069)
Homo sapiens (human)hBUB1, BUB1A
2B
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
3C, D
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E
(A)
waterwater18.016Chemie (HOH)
Sequence modifications
A: 724 - 1085 (UniProt: O43683)
PDBExternal DatabaseDetails
Gly 721-expression tag
Ser 722-expression tag
Pro 723-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41847.6
Non-Polymers*Number of molecules3
Total formula weight475.8
All*Total formula weight42323.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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