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4R7P

Human UDP-glucose pyrophosphorylase isoform 1 in complex with UDP-glucose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
UTP--glucose-1-phosphate uridylyltransferasepolymer52658952.24UniProt (Q16851)
Pfam (PF01704)
Homo sapiens (human)UDP-glucose pyrophosphorylase, UDPGP, UGPase
2E
(A)
URIDINE-5'-DIPHOSPHATE-GLUCOSEnon-polymer566.31Chemie (UPG)
3DA, EA, F, FA, G...
(C, A, D, B)
SULFATE IONnon-polymer96.115Chemie (SO4)
4GA, M, PA, QA
(C, A, D)
ACETATE IONnon-polymer59.04Chemie (ACT)
5HA, N, O, P, Q...
(C, A, D, B)
1,2-ETHANEDIOLnon-polymer62.111Chemie (EDO)
6AA, BA, CA, IA, JA...
(B, C, A, D)
ZINC IONnon-polymer65.411Chemie (ZN)
7UA, VA, WA, XA
(A, B, C, D)
waterwater18.0117Chemie (HOH)
Sequence modifications
A, B, C, D: 2 - 508 (UniProt: Q16851)
PDBExternal DatabaseDetails
Met -17-expression tag
Ala -16-expression tag
Ser -15-expression tag
Trp -14-expression tag
Ser -13-expression tag
His -12-expression tag
Pro -11-expression tag
Gln -10-expression tag
Phe -9-expression tag
Glu -8-expression tag
Lys -7-expression tag
Gly -6-expression tag
Ala -5-expression tag
Leu -4-expression tag
Val -3-expression tag
Pro -2-expression tag
Arg -1-expression tag
Gly 0-expression tag
Ser 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight235808.8
Non-Polymers*Number of molecules42
Total formula weight3645.7
All*Total formula weight239454.5
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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