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4QYL

Crystal Structure of the human BRPF1 bromodomain in complex with a histone H2AK5ac peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Peregrinpolymer11713720.74UniProt (P55201)
Pfam (PF00439)
Homo sapiens (human)Bromodomain and PHD finger-containing protein 1, Protein Br140
2E, F, G, H
(E, F, G, H)
Histone H2A type 1polymer121217.44UniProt (P0C0S8)Homo sapiensH2A.1, Histone H2A/p
3I, J, K, L
(A, B, C, D)
SULFATE IONnon-polymer96.14Chemie (SO4)
4M, N, O, P, Q...
(A, B, C, D, E...)
waterwater18.0722Chemie (HOH)
Sequence modifications
A, B, C, D: 4 - 117 (UniProt: P55201)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
Leu 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight59752.2
Non-Polymers*Number of molecules4
Total formula weight384.3
All*Total formula weight60136.4
*Water molecules are not included.

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PDB entries from 2025-06-25

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