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4QXU

Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(L)
anti_MT1-MMP Light chainpolymer21924124.71Mus musculus (mouse)
2B
(H)
anti_MT1-MMP Heavy chainpolymer23124995.11Mus musculus (mouse)
3C
(K)
Matrix metalloproteinase-14polymer111330.41UniProt (P50281)Homo sapiens (human)MMP-14, MMP-X1, Membrane-type matrix metalloproteinase 1, MT-MMP 1, MTMMP1, Membrane-type-1 matrix metalloproteinase, MT1-MMP, MT1MMP
4D, E
(H)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F, G
(L, H)
waterwater18.015Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight50450.2
Non-Polymers*Number of molecules2
Total formula weight192.1
All*Total formula weight50642.4
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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