4QXU

Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 H 301

Chain	Residue
H	SER52
H	GLY54
H	GLY55
H	ARG56

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 H 302

Chain	Residue
H	TYR127
H	LYS148
L	GLN129
L	SER132
L	GLY134

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site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR CHAIN K OF MATRIX METALLOPROTEINASE-14

Chain	Residue
H	ASN31
H	ALA33
H	THR50
H	SER52
H	GLY53
H	ASN57
H	TYR59
H	GLU99
H	ASN100
H	TYR101
H	GLY102
H	SER103
H	SER104
L	HIS31
L	ASN35
L	TYR37
L	LYS55
L	GLY96
L	TYR101
L	ASP148
L	LYS204

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR197-HIS203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9724659","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BQQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1BUV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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