4QKB
Crystal structure of seleno-methionine labelled human ALKBH7 in complex with alpha-ketoglutarate and Mn(II)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial | polymer | 200 | 22804.1 | 3 | UniProt (Q9BT30) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 7, Spermatogenesis cell proliferation-related protein, Spermatogenesis-associated protein 11 |
| 2 | D, F, G, H, J... (A, B, C) | MANGANESE (II) ION | non-polymer | 54.9 | 7 | Chemie (MN) | |||
| 3 | E, I, L (A, B, C) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 3 | Chemie (AKG) | |||
| 4 | N, O, P (A, B, C) | water | water | 18.0 | 54 | Chemie (HOH) |
Sequence modifications
A, B, C: 17 - 215 (UniProt: Q9BT30)
| PDB | External Database | Details |
|---|---|---|
| Mse 16 | - | expression tag |
| Mse 86 | Arg 86 | engineered mutation |
| Mse 89 | Leu 89 | engineered mutation |
| Arg 90 | Gln 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 68412.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 822.9 | |
| All* | Total formula weight | 69235.2 |
