4QK4
Crystal structure of human nuclear receptor sf-1 (nr5a1) bound to pip2 at 2.8 a resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Steroidogenic factor 1 | polymer | 245 | 27903.4 | 1 | UniProt (Q13285) Pfam (PF00104) In PDB | Homo sapiens (human) | SF-1, STF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP |
| 2 | B | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | polymer | 14 | 1523.9 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha, Ligand effect modulator 6 |
| 3 | A | (2S)-3-{[(R)-hydroxy{[(1R,2R,3S,4R,5R,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate | non-polymer | 971.0 | 1 | Chemie (PIK) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 218 - 461 (UniProt: Q13285)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 247 | Cys 247 | engineered mutation |
| Ser 412 | Cys 412 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29427.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1281.3 | |
| All* | Total formula weight | 30708.6 |
