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4QJZ

Pneumocystis carinii dihydrofolate reductase ternary complex with NADPH and the inhibitor 24, (N~6~-METHYL-N~6~-(NAPHTHALEN-1-YL)PYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1DDihydrofolate reductasepolymer20623918.51UniProt (P16184)
Pfam (PF00186)
In PDB
Pneumocystis carinii
2DN~6~-methyl-N~6~-(naphthalen-1-yl)pyrido[2,3-d]pyrimidine-2,4,6-triaminenon-polymer316.41Chemie (33M)
3DNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.41Chemie (NDP)
4waterwater18.079Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23918.5
Non-Polymers*Number of molecules2
Total formula weight1061.8
All*Total formula weight24980.3
*Water molecules are not included.

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PDB entries from 2024-09-11

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