4QJZ
Pneumocystis carinii dihydrofolate reductase ternary complex with NADPH and the inhibitor 24, (N~6~-METHYL-N~6~-(NAPHTHALEN-1-YL)PYRIDO[2,3-D]PYRIMIDINE-2,4,6-TRIAMINE)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Dihydrofolate reductase | polymer | 206 | 23918.5 | 1 | UniProt (P16184) | Pneumocystis carinii | |
| 2 | B (D) | N~6~-methyl-N~6~-(naphthalen-1-yl)pyrido[2,3-d]pyrimidine-2,4,6-triamine | non-polymer | 316.4 | 1 | Chemie (33M) | |||
| 3 | C (D) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 1 | Chemie (NDP) | |||
| 4 | D (D) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23918.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1061.8 | |
| All* | Total formula weight | 24980.3 |
