4QGT
The Crystal Structure of Human IgG Fc Domain with Enhanced Aromatic Sequon
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Hepatitis B virus receptor binding protein | polymer | 233 | 26232.8 | 2 | UniProt (Q6PYX1) Pfam (PF07654) In PDB | Homo sapiens (human) | |
| 2 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 951.9 | 1 | In PDB GlyTouCan (G12045WP) | |||
| 3 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1463.3 | 1 | In PDB GlyTouCan (G80858MF) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 216 - 447 (UniProt: Q6PYX1)
| PDB | External Database | Details |
|---|---|---|
| Phe 215 | - | expression tag |
| Phe 295 | Gln 196 | engineered mutation |
| Ala 296 | Tyr 197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 52465.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 2415.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 54972.9 |
