4QF9
Structure of GluK1 ligand-binding domain (S1S2) in complex with (S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid at 2.28 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor ionotropic, kainate 1 | polymer | 257 | 29108.5 | 3 | UniProt (P22756) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (brown rat rat rats) | GluK1, Glutamate receptor 5, GluR-5, GluR5 |
| 2 | D, H, O (A, B, C) | (2S)-2-amino-4-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-6-yl)butanoic acid | non-polymer | 263.2 | 3 | Chemie (35K) | |||
| 3 | E, I, J, P (A, B, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | F, N (A, B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 2 | Chemie (PG4) | |||
| 5 | G (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | K, L, M (B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 7 | Q (C) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 8 | R, S, T (A, B, C) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A, B, C: 2 - 116 (UniProt: P22756)
A, B, C: 119 - 257 (UniProt: P22756)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | linker |
| Thr 118 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87325.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1933.2 | |
| All* | Total formula weight | 89258.6 |
