4QEX

Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217

Replaces:  4K4M

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Erythrocyte-binding antigen-175	polymer	602	72184.4	2	UniProt (Q05644) Pfam (PF05424) In PDB	Plasmodium falciparum
2	L, M	Antibody Light Chain	polymer	214	23623.0	2		Mus musculus (mouse)
3	H, I	Antibody Heavy Chain	polymer	215	22897.4	2		Mus musculus (mouse)

Sequence modifications

A, B: 1 - 602 (UniProt: Q05644)

PDB	External Database	Details
Gln 3	Asn 147	ENGINEERED MUTATION
Ala 50	Ser 194	ENGINEERED MUTATION
Ala 195	Ser 339	ENGINEERED MUTATION
Ala 206	Thr 350	ENGINEERED MUTATION

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	237409.7
All*	Total formula weight	237409.7

*Water molecules are not included.