4QEX
Crystal structure of PfEBA-175 RII in complex with a Fab fragment from inhibitory antibody R217
Replaces: 4K4MEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Erythrocyte-binding antigen-175 | polymer | 602 | 72184.4 | 2 | UniProt (Q05644) Pfam (PF05424) | Plasmodium falciparum | |
| 2 | B, E (L, M) | Antibody Light Chain | polymer | 214 | 23623.0 | 2 | Mus musculus (mouse) | ||
| 3 | C, F (H, I) | Antibody Heavy Chain | polymer | 215 | 22897.4 | 2 | Mus musculus (mouse) |
Sequence modifications
A, B: 1 - 602 (UniProt: Q05644)
| PDB | External Database | Details |
|---|---|---|
| Gln 3 | Asn 147 | engineered mutation |
| Ala 50 | Ser 194 | engineered mutation |
| Ala 195 | Ser 339 | engineered mutation |
| Ala 206 | Thr 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 237409.7 | |
| All* | Total formula weight | 237409.7 |
