4Q33

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and A110

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Inosine-5'-monophosphate dehydrogenase	polymer	363	38441.3	8	UniProt (Q0TN42) Pfam (PF00478) UniProt (by SIFTS) (A0A0H2YRZ7)	Clostridium perfringens	IMP dehydrogenase, IMPD, IMPDH
2	CA, FA, I, K, N... (G, H, A, B, C...)	INOSINIC ACID	non-polymer		348.2	8	Chemie (IMP)
3	DA, GA, J, L, M... (G, H, A, B, C...)	4-[(1R)-1-[1-(4-chlorophenyl)-1,2,3-triazol-4-yl]ethoxy]-1-oxidanyl-quinoline	non-polymer		366.8	8	Chemie (2YA)
4	Q (D)	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
5	AA, EA, HA, IA, T... (F, G, H, E)	FORMIC ACID	non-polymer		46.0	7	Chemie (FMT)
6	U (E)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7	BA, Y (F)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
8	JA, KA, LA, MA, NA... (A, B, C, D, E...)	water	water		18.0	137	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 88 (UniProt: Q0TN42)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B, C, D, E, F, G, H: 216 - 484 (UniProt: Q0TN42)

PDB	External Database	Details
Ser 89	-	linker
Gly 90	-	linker
Gly 91	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	307530.1
Non-Polymers*	Number of molecules	27
	Total formula weight	6382.5
All*	Total formula weight	313912.7

*Water molecules are not included.