4Q0A

Vitamin D Receptor complex with lithocholic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C	Vitamin D3 receptor A	polymer	302	34060.7	1	UniProt (Q9PTN2) Pfam (PF00104) In PDB	Danio rerio (leopard danio zebra danio zebra fish)	VDR-A, 1,25-dihydroxyvitamin D3 receptor A, Nuclear receptor subfamily 1 group I member 1-A
2	D	Nuclear receptor coactivator 2	polymer	10	1218.5	1	UniProt (Q15596) In PDB	Homo sapiens	NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3	C	(3beta,5beta,14beta,17alpha)-3-hydroxycholan-24-oic acid	non-polymer		376.6	2	Chemie (4OA)
4		water	water		18.0	87	Chemie (HOH)

Sequence modifications

C: 156 - 453 (UniProt: Q9PTN2)

PDB	External Database	Details
Gly 152	-	expression tag
Ser 153	-	expression tag
His 154	-	expression tag
Met 155	-	expression tag

D: 688 - 696 (UniProt: Q15596)

PDB	External Database	Details
Gly 687	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35279.2
Non-Polymers*	Number of molecules	2
	Total formula weight	753.1
All*	Total formula weight	36032.3

*Water molecules are not included.