4PY4
Crystal structure of human poly(ADP-ribose) polymerase 14, catalytic domain in complex with an inhibitor XL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Poly [ADP-ribose] polymerase 14 | polymer | 189 | 21654.0 | 2 | UniProt (Q460N5) Pfam (PF00644) | Homo sapiens (human) | PARP-14, ADP-ribosyltransferase diphtheria toxin-like 8, ARTD8, B aggressive lymphoma protein 2 |
| 2 | C, D (A, B) | 2-({4-[(1R)-1-(dimethylamino)ethyl]phenyl}amino)-6-fluoro-1,3-benzothiazole-4-carboxamide | non-polymer | 358.4 | 2 | Chemie (XL2) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43308.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 716.9 | |
| All* | Total formula weight | 44024.9 |
