4PXU

Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bipolar kinesin KRP-130	polymer	211	24233.4	2	UniProt (P46863)	Drosophila melanogaster (Fruit fly)	Kinesin-like protein Klp61F
2	C (B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
3	D, E (A, B)	water	water		18.0	60	Chemie (HOH)

Sequence modifications

A, B: 634 - 839 (UniProt: P46863)

PDB	External Database	Details
Met 633	-	expression tag
Ser 836	His 836	engineered mutation
Gly 837	His 837	engineered mutation
His 840	-	expression tag
His 841	-	expression tag
His 840	-	expression tag
His 841	-	expression tag
His 842	-	expression tag
His 843	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48466.8
Non-Polymers*	Number of molecules	1
	Total formula weight	118.2
All*	Total formula weight	48585.0

*Water molecules are not included.