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4PVF

Crystal structure of Homo sapiens holo serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), isoform 3, transcript variant 5, 483 aa, at 2.6 ang. resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Serine hydroxymethyltransferase, mitochondrialpolymer48353754.92UniProt (P34897)
Pfam (PF00464)
Homo sapiens (human)SHMT, Glycine hydroxymethyltransferase, Serine methylase
2C, E
(A, B)
GLYCEROLnon-polymer92.12Chemie (GOL)
3D
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
4F, G
(A, B)
waterwater18.0126Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight107509.9
Non-Polymers*Number of molecules3
Total formula weight290.3
All*Total formula weight107800.2
*Water molecules are not included.

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PDB entries from 2025-02-05

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