4PUF

Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	E3 ubiquitin-protein ligase SlrP	polymer	637	72967.6	2	UniProt (D0ZRB2) Pfam (PF12468) Pfam (PF14496)	Salmonella enterica subsp. enterica serovar Typhimurium	Secreted effector protein SlrP
2	C, D (C, D)	Thioredoxin	polymer	117	13156.0	2	UniProt (P10599) Pfam (PF00085)	Homo sapiens (human)	Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP

Sequence modifications

A, B: 141 - 765 (UniProt: D0ZRB2)

PDB	External Database	Details
Met 129	-	expression tag
Arg 130	-	expression tag
Gly 131	-	expression tag
Ser 132	-	expression tag
His 133	-	expression tag
His 134	-	expression tag
His 135	-	expression tag
His 136	-	expression tag
His 137	-	expression tag
His 138	-	expression tag
Gly 139	-	expression tag
Ser 140	-	expression tag

C, D: 1 - 105 (UniProt: P10599)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	172247.1
All*	Total formula weight	172247.1

*Water molecules are not included.