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4PAN

A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440415.01UniProt (P10824)
Pfam (PF00503)
Rattus norvegicus (Rat)Adenylate cyclase-inhibiting G alpha protein
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
SULFITE IONnon-polymer80.11Chemie (SO3)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5E
(A)
waterwater18.088Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P10824)
PDBExternal DatabaseDetails
Tyr 336Phe 336engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40415.0
Non-Polymers*Number of molecules3
Total formula weight558.7
All*Total formula weight40973.7
*Water molecules are not included.

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PDB entries from 2024-10-30

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