4P0V
Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Farnesyl pyrophosphate synthase | polymer | 347 | 39915.6 | 1 | UniProt (P14324) Pfam (PF00348) | Homo sapiens (Human) | FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase |
| 2 | B (A) | ZOLEDRONIC ACID | non-polymer | 272.1 | 1 | Chemie (ZOL) | |||
| 3 | C (A) | (5beta)-11-hydroxyabieta-7,9(11),13-triene-6,12-dione | non-polymer | 314.4 | 1 | Chemie (1WO) | |||
| 4 | D, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G (A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39915.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 659.4 | |
| All* | Total formula weight | 40575.0 |
