4P0V
Crystal structure of human farnesyl diphosphoate synthase in complex with zoledronate and taxodione
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | SYNCHROTRON |
Source details | APS BEAMLINE 21-ID-F |
Synchrotron site | APS |
Beamline | 21-ID-F |
Temperature [K] | 300 |
Detector technology | CCD |
Collection date | 2013-12-13 |
Detector | MARMOSAIC 225 mm CCD |
Wavelength(s) | 0.97872 |
Spacegroup name | P 41 21 2 |
Unit cell lengths | 112.143, 112.143, 67.053 |
Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
Resolution | 79.300 - 2.400 |
R-factor | 0.2062 |
Rwork | 0.202 |
R-free | 0.29250 |
RMSD bond length | 0.014 |
RMSD bond angle | 1.575 |
Refinement software | REFMAC (5.8.0049) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 79.300 |
High resolution limit [Å] | 2.400 |
Number of reflections | 17015 |
<I/σ(I)> | 29.78 |
Completeness [%] | 98.5 |
Redundancy | 8.1 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 | VAPOR DIFFUSION, HANGING DROP | 5 | 293 | 1.2M sodium potassium phosphate, 25% glycerol |