4OZT
crystal structure of the ligand binding domains of the Bovicola ovis ecdysone receptor EcR/USP heterodimer (PonA crystal)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Ecdysone receptor | polymer | 238 | 27482.6 | 1 | UniProt (E0VVT4) Pfam (PF00104) | Pediculus humanus subsp. corporis (Body louse) | |
| 2 | B (U) | Retinoid X receptor | polymer | 195 | 21977.5 | 1 | UniProt (E0VFQ5) Pfam (PF00104) | Pediculus humanus subsp. corporis (Body louse) | |
| 3 | C (E) | 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE | non-polymer | 464.6 | 1 | Chemie (P1A) | |||
| 4 | D (U) | N-ETHYLMALEIMIDE | non-polymer | 125.1 | 1 | Chemie (NEQ) | |||
| 5 | E, F (E, U) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
E: 281 - 518 (UniProt: E0VVT4)
U: 196 - 390 (UniProt: E0VFQ5)
| PDB | External Database | Details |
|---|---|---|
| Thr 316 | Ala 316 | conflict |
| Ala 472 | Arg 472 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ser 207 | Thr 233 | conflict |
| Ser 302 | Cys 328 | conflict |
| Lys 373 | Arg 399 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49460.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 589.8 | |
| All* | Total formula weight | 50049.9 |
