4OZT

crystal structure of the ligand binding domains of the Bovicola ovis ecdysone receptor EcR/USP heterodimer (PonA crystal)

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0003677	molecular_function	DNA binding
E	0004879	molecular_function	nuclear receptor activity
E	0005634	cellular_component	nucleus
E	0006355	biological_process	regulation of DNA-templated transcription
E	0035076	biological_process	ecdysone receptor signaling pathway
E	0035100	molecular_function	ecdysone binding
U	0003677	molecular_function	DNA binding
U	0003707	molecular_function	nuclear steroid receptor activity
U	0005634	cellular_component	nucleus
U	0006355	biological_process	regulation of DNA-templated transcription
U	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue P1A E 601

Chain	Residue
E	GLU303
E	PHE389
E	ALA390
E	TYR400
E	LEU412
E	ASN494
E	HOH708
E	PRO305
E	ILE331
E	ILE334
E	THR335
E	THR338
E	MET372
E	ARG375
E	MET376

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site_id	AC2
Number of Residues	8
Details	binding site for residue NEQ U 401

Chain	Residue
E	ARG294
U	GLY274
U	GLY276
U	THR277
U	CYS365
U	GLU367
U	LEU369
U	HOH520

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