4OYS
CRYSTAL STRUCTURE OF VPS34 IN COMPLEX WITH SAR405.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 3-kinase catalytic subunit type 3 | polymer | 601 | 68597.4 | 1 | UniProt (Q8NEB9) Pfam (PF00613) Pfam (PF00454) In PDB | Homo sapiens (Human) | PtdIns-3-kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34 |
| 2 | A | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A | (8S)-9-[(5-chloranylpyridin-3-yl)methyl]-2-[(3R)-3-methylmorpholin-4-yl]-8-(trifluoromethyl)-6,7,8,9a-tetrahydro-3H-pyrimido[1,2-a]pyrimidin-4-one | non-polymer | 445.9 | 1 | Chemie (1TT) | |||
| 4 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 282 - 879 (UniProt: Q8NEB9)
| PDB | External Database | Details |
|---|---|---|
| Gly 279 | - | expression tag |
| Ala 280 | - | expression tag |
| Met 281 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 68597.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 830.1 | |
| All* | Total formula weight | 69427.5 |
