4OL8

Ty3 reverse transcriptase bound to DNA/RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H (A, B, F, E)	Reverse transcriptase/ribonuclease H	polymer	478	55059.4	4	UniProt (Q99315) Pfam (PF00078) Pfam (PF17919)	Saccharomyces cerevisiae (Baker's yeast)	Ty3 reverse transcriptase, RT, RT-RH, p55
2	C, E (C, G)	5'-R(*CP*UP*GP*AP*GP*AP*GP*AP*GP*AP*GP*GP*AP*AP*GP*AP*UP*G)-3'	polymer	18	5938.6	2
3	D, F (D, H)	5'-D(*CP*AP*TP*CP*TP*TP*CP*CP*TP*CP*TP*CP*TP*CP*TP*C)-3'	polymer	16	4711.1	2
4	I, J (B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	K (B)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B, F, E: 1 - 476 (UniProt: Q99315)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag
Asn 426	Asp 961	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	241537.2
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	241729.3

*Water molecules are not included.