4ODO

Structure of SlyD from Thermus thermophilus in complex with FK506

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Peptidyl-prolyl cis-trans isomerase SlyD	polymer	158	17400.2	3	UniProt (Q5SLE7) Pfam (PF00254) In PDB	Thermus thermophilus (human)	TtSlyD
2	A, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	A, B, C	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
4	A, B, C	8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN	non-polymer		804.0	3	Chemie (FK5)
5	B	2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		209.2	1	Chemie (BTB)
6	C	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
7		water	water		18.0	629	Chemie (HOH)

Sequence modifications

A, B, C: 1 - 149 (UniProt: Q5SLE7)

PDB	External Database	Details
Pro 150	-	expression tag
Ser 151	-	expression tag
Gly 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag
His 156	-	expression tag
His 157	-	expression tag
His 158	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	52200.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2917.0
All*	Total formula weight	55117.7

*Water molecules are not included.