4ODO
Structure of SlyD from Thermus thermophilus in complex with FK506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Peptidyl-prolyl cis-trans isomerase SlyD | polymer | 158 | 17400.2 | 3 | UniProt (Q5SLE7) Pfam (PF00254) | Thermus thermophilus (human) | TtSlyD |
| 2 | D, E, F, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 3 | G, I, M (A, B, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) PubChem (312) | |||
| 4 | H, K, O (A, B, C) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 3 | Chemie (FK5) PubChem (23377000) PubChem (177746942) PubChem (23308325) PubChem (23581796) PubChem (24978521) PubChem (54611630) PubChem (57206900) PubChem (44294761) PubChem (44314852) PubChem (403209) PubChem (439492) PubChem (59042420) PubChem (59111253) PubChem (59112447) PubChem (59118415) PubChem (44575549) PubChem (59746606) PubChem (46783859) PubChem (59917266) PubChem (59918741) PubChem (60086106) PubChem (46781577) PubChem (66509027) PubChem (66672804) PubChem (49874294) PubChem (71296869) PubChem (71316759) PubChem (71668407) PubChem (73265325) PubChem (57417278) PubChem (57892354) PubChem (57910335) PubChem (58584114) PubChem (59032416) PubChem (58946030) PubChem (59141120) PubChem (59049316) PubChem (59974193) PubChem (59993548) PubChem (60035606) PubChem (66709866) PubChem (67340654) PubChem (67626881) PubChem (68219140) PubChem (68712665) PubChem (69247758) PubChem (176478128) PubChem (89068341) PubChem (176856280) PubChem (177675132) PubChem (5372) PubChem (64779) PubChem (445643) PubChem (77906388) PubChem (89249909) PubChem (89545901) PubChem (89960652) PubChem (5353987) PubChem (145857191) PubChem (117646237) PubChem (6426916) PubChem (6436007) PubChem (6473866) PubChem (123552884) PubChem (5472317) PubChem (9832283) PubChem (9853905) PubChem (125039862) PubChem (9918805) PubChem (125136698) PubChem (125136697) PubChem (9963169) PubChem (129009965) PubChem (129010422) PubChem (130330191) PubChem (131676819) PubChem (6536850) PubChem (6610362) PubChem (6912836) PubChem (133562888) PubChem (133688365) PubChem (11556866) PubChem (134694629) PubChem (9940643) PubChem (12134936) PubChem (13006299) PubChem (137705868) PubChem (138106951) PubChem (138574020) PubChem (124511204) PubChem (140494820) PubChem (13819070) PubChem (140647114) PubChem (13819074) PubChem (13819069) PubChem (140893615) PubChem (13819073) PubChem (149048732) PubChem (125039860) PubChem (125039861) PubChem (125136699) PubChem (125136700) PubChem (160433486) PubChem (162711219) PubChem (163027397) PubChem (163027399) PubChem (163027400) PubChem (125182986) PubChem (126687738) PubChem (166023667) PubChem (168312998) PubChem (170277719) PubChem (171042252) PubChem (171360199) PubChem (172042935) PubChem (173882479) PubChem (129606865) PubChem (131668141) PubChem (137546410) PubChem (137546581) PubChem (138574025) PubChem (139032034) PubChem (140652196) PubChem (143265740) PubChem (144640477) PubChem (146323807) PubChem (156417380) PubChem (156528350) PubChem (160433487) PubChem (163027398) PubChem (163027401) PubChem (163027402) PubChem (167413568) PubChem (170997009) PubChem (171122179) PubChem (171137683) PubChem (171156312) PubChem (171322980) PubChem (171329370) PubChem (172634670) PubChem (175667550) | |||
| 5 | J (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) PubChem (81462) | |||
| 6 | N (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 7 | P, Q, R (A, B, C) | water | water | 18.0 | 629 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 149 (UniProt: Q5SLE7)
| PDB | External Database | Details |
|---|---|---|
| Pro 150 | - | expression tag |
| Ser 151 | - | expression tag |
| Gly 152 | - | expression tag |
| His 153 | - | expression tag |
| His 154 | - | expression tag |
| His 155 | - | expression tag |
| His 156 | - | expression tag |
| His 157 | - | expression tag |
| His 158 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 52200.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2917.0 | |
| All* | Total formula weight | 55117.7 |
