4ODO

Structure of SlyD from Thermus thermophilus in complex with FK506

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0016853	molecular_function	isomerase activity
A	0042026	biological_process	protein refolding
A	0046872	molecular_function	metal ion binding
B	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
B	0003824	molecular_function	catalytic activity
B	0005737	cellular_component	cytoplasm
B	0016853	molecular_function	isomerase activity
B	0042026	biological_process	protein refolding
B	0046872	molecular_function	metal ion binding
C	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0016853	molecular_function	isomerase activity
C	0042026	biological_process	protein refolding
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 201

Chain	Residue
A	GLU112
A	HOH351
A	HOH377
B	HOH310
B	HOH313
B	HOH366

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 202

Chain	Residue
A	HOH361
A	HOH366
A	HOH370
A	HOH301
A	HOH347
A	HOH353

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 203

Chain	Residue
A	HOH333
A	HOH443
A	HOH478
A	HOH479
A	HOH480
A	HOH519

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 204

Chain	Residue
A	TYR29
A	LEU30
A	ASN35
A	HIS147
A	ALA148

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FK5 A 205

Chain	Residue
A	TYR13
A	LEU15
A	ASP23
A	ASN35
A	LEU36
A	ILE37
A	LEU40
A	ALA62
A	TYR63
A	LEU121
A	HOH398
A	HOH426
A	HOH432
C	ARG12
C	GLU26

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL B 201

Chain	Residue
B	TYR29
B	LEU30
B	ASN35
B	HIS147
B	ALA148

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE BTB B 202

Chain	Residue
B	ASN35
B	HIS147
B	FK5203
B	HOH368
B	HOH386
B	HOH426
C	GLN72
C	ALA93
C	GLN94
C	PHE117

---

site_id	AC8
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FK5 B 203

Chain	Residue
B	TYR13
B	LEU15
B	ASP23
B	ASN35
B	LEU36
B	ILE37
B	LEU40
B	ALA62
B	TYR63
B	LEU121
B	PHE128
B	BTB202
B	HOH341
B	HOH396
B	HOH434
B	HOH444
B	HOH493
C	ALA78
C	ASP95
C	GLY98
C	GOL203
C	HOH304

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 201

Chain	Residue
B	HOH385
C	SER77
C	HOH319
C	HOH381
C	HOH385
C	HOH419

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL C 202

Chain	Residue
C	TYR29
C	LEU30
C	ASN35
C	HIS147
C	ALA148

---

site_id	BC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL C 203

Chain	Residue
B	FK5203
C	ALA78
C	PHE79
C	PRO80
C	TYR92
C	ALA93
C	HOH304
C	HOH333
C	HOH353
C	HOH400

---

site_id	BC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE FK5 C 204

Chain	Residue
C	LEU15
C	ASP23
C	ASN35
C	LEU36
C	ILE37
C	LEU40
C	ALA62
C	TYR63
C	PHE128
C	HOH354
C	HOH407
C	HOH436
A	TYR92
A	GLN94
C	TYR13

---