4O9S
Crystal structure of Retinol-Binding Protein 4 (RBP4)in complex with a non-retinoid ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Retinol-binding protein 4 | polymer | 215 | 24958.9 | 2 | UniProt (P02753) Pfam (PF00061) In PDB | Homo sapiens (human) | Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176) |
2 | A, B | 1-[4-(7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),2(6),8,10-tetraen-12-yl)piperazin-1-yl]-2-[2-(trifluoromethyl)phenyl]ethanone | non-polymer | 446.5 | 2 | Chemie (2RY) | |||
3 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 26 | Chemie (EDO) | |||
4 | B, A | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
6 | water | water | 18.0 | 231 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 183 (UniProt: P02753)
PDB | External Database | Details |
---|---|---|
His -31 | - | expression tag |
Ile -30 | - | expression tag |
Ser -29 | - | expression tag |
Met -28 | - | expression tag |
Ala -27 | - | expression tag |
Ser -26 | - | expression tag |
Met -25 | - | expression tag |
Ser -24 | - | expression tag |
Tyr -23 | - | expression tag |
Tyr -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
Asp -15 | - | expression tag |
Tyr -14 | - | expression tag |
Asp -13 | - | expression tag |
Ile -12 | - | expression tag |
Pro -11 | - | expression tag |
Thr -10 | - | expression tag |
Thr -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Gly -2 | - | expression tag |
Ala -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 49917.7 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 2719.2 | |
All* | Total formula weight | 52636.9 |