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4O68

Structure of human cyclic GMP-AMP synthase (cGAS)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cyclic GMP-AMP synthasepolymer37643850.61UniProt (Q8N884)
Pfam (PF03281)
Pfam (PF20266)
Homo sapiens (human)cGAMP synthase, cGAS, h-cGAS, Mab-21 domain-containing protein 1
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
waterwater18.090Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight43850.6
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight43916.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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