4O2B
Tubulin-Colchicine complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha-1B chain | polymer | 451 | 50204.4 | 2 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | Bos taurus (bovine) | Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain |
| 2 | B, D (B, D) | Tubulin beta-2B chain | polymer | 445 | 49999.9 | 2 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | Bos taurus (bovine) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16844.2 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (rat) | Stathmin-like protein B3, RB3 |
| 4 | F (F) | Tubulin-tyrosine ligase | polymer | 384 | 44378.5 | 1 | UniProt (E1BQ43) | Gallus gallus (chicken) | |
| 5 | G, V (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 6 | H, HA, MA, N, W (A, D, F, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 7 | I, J, JA, K, KA... (A, D, E, B, C) | GLYCEROL | non-polymer | 92.1 | 13 | Chemie (GOL) | |||
| 8 | CA, L, T (C, A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 9 | GA, M (D, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 10 | IA, O (D, B) | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | non-polymer | 399.4 | 2 | Chemie (LOC) | |||
| 11 | U (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 12 | AA, BA (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 13 | DA, EA, FA (C) | IMIDAZOLE | non-polymer | 69.1 | 3 | Chemie (IMD) | |||
| 14 | NA (F) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 1 | Chemie (ACP) | |||
| 15 | OA, PA, QA, RA, SA... (A, B, C, D, E...) | water | water | 18.0 | 626 | Chemie (HOH) |
Sequence modifications
E: 5 - 145 (UniProt: P63043)
F: 1 - 378 (UniProt: E1BQ43)
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | cloning artifact |
| Ala 4 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| His 379 | - | expression tag |
| His 380 | - | expression tag |
| His 381 | - | expression tag |
| His 382 | - | expression tag |
| His 383 | - | expression tag |
| His 384 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261631.3 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 5290.6 | |
| All* | Total formula weight | 266921.9 |
