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4NZ7

Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p): RNA binding, activity, and atomic model

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
tRNA pseudouridine synthase A, mitochondrialpolymer31335626.91UniProt (Q9Y606)
Pfam (PF01416)
Homo sapiens (human)tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I
2B
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
3C
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
4D
(A)
waterwater18.0108Chemie (HOH)
Sequence modifications
A: 83 - 394 (UniProt: Q9Y606)
PDBExternal DatabaseDetails
Ser 82-expression tag
Ala 146Asp 146engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35626.9
Non-Polymers*Number of molecules2
Total formula weight388.5
All*Total formula weight36015.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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