4NZ7

Steroid receptor RNA Activator (SRA) modification by the human Pseudouridine Synthase 1 (hPus1p): RNA binding, activity, and atomic model

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001522	biological_process	pseudouridine synthesis
A	0003723	molecular_function	RNA binding
A	0009451	biological_process	RNA modification
A	0009982	molecular_function	pseudouridine synthase activity
A	0031119	biological_process	tRNA pseudouridine synthesis

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EPE A 401

Chain	Residue
A	ARG144
A	HOH598
A	THR145
A	ALA146
A	VAL149
A	TYR201
A	PHE289
A	MET291
A	LEU333
A	HOH559

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PGE A 402

Chain	Residue
A	LEU174
A	LEU174
A	SER176
A	SER176
A	ARG179
A	ARG179

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"24722331","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ITS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4NZ6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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