4NWU

Crystal structure of APE1551, an anti-human NGF Fab with a nine amino acid insertion in CDR H1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	APE1551 Ab Fab heavy chain	polymer	242	25965.8	1	UniProt (P01857) Pfam (PF07654)	Homo sapiens (human)
2	B (L)	APE1551 Ab Fab light chain	polymer	220	24342.9	1	UniProt (Q8TCD0)	Homo sapiens (human)
3	C, D (H, L)	water	water		18.0	434	Chemie (HOH)

Sequence modifications

H: 1 - 121 (PDB: 4NWU)
H: 122 - 232 (UniProt: P01857)
L: 1 - 105 (PDB: 4NWU)
L: 106 - 214 (UniProt: Q8TCD0)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50308.7
All*	Total formula weight	50308.7

*Water molecules are not included.