4NWT

Crystal structure of the anti-human NGF Fab APE1531

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	L	APE1531 Ab Fab light chain	polymer	220	24342.9	1	UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) In PDB	Homo sapiens (human)
2	H	APE1531 Ab Fab heavy chain	polymer	233	24950.8	1	UniProt (P01857) Pfam (PF07654) In PDB	Homo sapiens (human)
3	L	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
4	L, H	ACETATE ION	non-polymer		59.0	4	Chemie (ACT)
5	H	TRIETHYLENE GLYCOL	non-polymer		150.2	1	Chemie (PGE)
6		water	water		18.0	373	Chemie (HOH)

Sequence modifications

L: 1 - 105 (PDB: 4NWT)
L: 106 - 214 (UniProt: Q8TCD0)
H: 1 - 101 (PDB: 4NWT)
H: 122 - 220 (UniProt: P01857)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49293.7
Non-Polymers*	Number of molecules	7
	Total formula weight	776.8
All*	Total formula weight	50070.5

*Water molecules are not included.