4NWT
Crystal structure of the anti-human NGF Fab APE1531
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | APE1531 Ab Fab light chain | polymer | 220 | 24342.9 | 1 | UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (H) | APE1531 Ab Fab heavy chain | polymer | 233 | 24950.8 | 1 | UniProt (P01857) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C, D (L) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 4 | E, F, G, H (L, H) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 5 | I (H) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | J, K (L, H) | water | water | 18.0 | 373 | Chemie (HOH) |
Sequence modifications
L: 1 - 105 (PDB: 4NWT)
L: 106 - 214 (UniProt: Q8TCD0)
H: 1 - 101 (PDB: 4NWT)
H: 122 - 220 (UniProt: P01857)
L: 106 - 214 (UniProt: Q8TCD0)
H: 1 - 101 (PDB: 4NWT)
H: 122 - 220 (UniProt: P01857)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49293.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 776.8 | |
| All* | Total formula weight | 50070.5 |
