4NRU

Murine Norovirus RNA-dependent-RNA-polymerase in complex with Compound 6, a suramin derivative

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	RNA dependent RNA polymerase	polymer	515	58435.4	6	UniProt (S4V9Y7) Pfam (PF00680) UniProt (by SIFTS) (Q80J95)	Murine norovirus 1
2	G, I, K, M, O... (A, B, C, D, E...)	4-({4-methyl-3-[(3-nitrobenzoyl)amino]benzoyl}amino)naphthalene-1,5-disulfonic acid	non-polymer		585.6	7	Chemie (2NG)
3	H, J, L, N, Q... (A, B, C, D, E...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	T, U, V, W, X... (A, B, C, D, E...)	water	water		18.0	1714	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 507 (UniProt: S4V9Y7)

PDB	External Database	Details
Leu 508	-	expression tag
Glu 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag
His 515	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	350612.5
Non-Polymers*	Number of molecules	13
	Total formula weight	4244.8
All*	Total formula weight	354857.3

*Water molecules are not included.