4NLW
Poliovirus Polymerase - G289A/C290I Loop Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase 3D-POL | polymer | 461 | 52803.9 | 1 | UniProt (P03300) Pfam (PF00680) | Human poliovirus 1 | P3D-POL, Genome polyprotein |
| 2 | B, C, D, E, F (A) | ACETIC ACID | non-polymer | 60.1 | 5 | Chemie (ACY) | |||
| 3 | G, H (A) | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
| 4 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | J (A) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 1 - 461 (UniProt: P03300)
| PDB | External Database | Details |
|---|---|---|
| Ala 289 | Gly 2037 | engineered mutation |
| Ile 290 | Cys 2038 | engineered mutation |
| Asp 446 | Leu 2194 | engineered mutation |
| Asp 455 | Arg 2203 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 52803.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 799.8 | |
| All* | Total formula weight | 53603.7 |
