4NLC

Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei, mutant C496S

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Ribosomal RNA processing protein 6	polymer	373	42453.7	1	UniProt (Q581R8) Pfam (PF01612) Pfam (PF00570) In PDB	Trypanosoma brucei brucei
2	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
3		water	water		18.0	212	Chemie (HOH)

Sequence modifications

A: 176 - 540 (UniProt: Q581R8)

PDB	External Database	Details
Ser 496	Cys 496	engineered mutation
Leu 541	-	expression tag
Glu 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42453.7
Non-Polymers*	Number of molecules	2
	Total formula weight	212.2
All*	Total formula weight	42666.0

*Water molecules are not included.