4NLC
Crystal structure of the catalytic core of RRP6 from Trypanosoma brucei, mutant C496S
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| A | 0000467 | biological_process | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0044237 | biological_process | cellular metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 601 |
| Chain | Residue |
| A | TYR280 |
| A | PRO443 |
| A | HIS444 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG A 602 |
| Chain | Residue |
| A | PHE195 |
| A | ARG196 |
| A | VAL198 |
| A | LYS335 |
| A | ASP336 |
| A | HOH727 |
