4NHC
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | FAB LIGHT CHAIN | polymer | 215 | 23395.8 | 1 | Homo sapiens | ||
| 2 | B (H) | FAB HEAVY CHAIN | polymer | 228 | 23990.0 | 1 | Homo sapiens | ||
| 3 | C (P) | MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41) | polymer | 17 | 2089.6 | 1 | BIRD (PRD_001209) | ||
| 4 | D, F (L, H) | trifluoroacetic acid | non-polymer | 114.0 | 2 | Chemie (TFA) | |||
| 5 | E (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | G, H, I (L, H, P) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 49475.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 323.0 | |
| All* | Total formula weight | 49798.5 |
