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4NHA

Structure of human Dicer Platform-PAZ-Connector Helix cassette in complex with 16-mer siRNA having 5'-p and UU-3' ends (3.4 Angstrom resolution)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Endoribonuclease Dicerpolymer30235232.11UniProt (Q9UPY3)
Pfam (PF20931)
Pfam (PF02170)
Homo sapiens (human)Helicase with RNase motif, Helicase MOI
2B
(B)
5'-R(P*GP*CP*GP*UP*UP*GP*GP*CP*CP*AP*AP*CP*GP*CP*UP*U)-3'polymer165090.11
Sequence modifications
A: 755 - 1055 (UniProt: Q9UPY3)
PDBExternal DatabaseDetails
Ser 754-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40322.2
All*Total formula weight40322.2
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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