4NDF
Human Aprataxin (Aptx) bound to RNA-DNA, AMP, and Zn - product complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aprataxin | polymer | 182 | 21259.8 | 2 | UniProt (Q7Z2E3) Pfam (PF11969) Pfam (PF16278) | Homo sapiens (human) | Forkhead-associated domain histidine triad-like protein, FHA-HIT |
| 2 | C, E (D, G) | 5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3' | polymer | 10 | 3066.0 | 2 | |||
| 3 | D, F (E, H) | 5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3' | polymer | 10 | 3037.0 | 2 | |||
| 4 | G, K (A, B) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 2 | Chemie (AMP) | |||
| 5 | H, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | J, M (A, B) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 2 | Chemie (BME) | |||
| 8 | N (E) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 9 | O, P, Q, R, S... (A, B, D, E, G...) | water | water | 18.0 | 556 | Chemie (HOH) |
Sequence modifications
A, B: 165 - 342 (UniProt: Q7Z2E3)
| PDB | External Database | Details |
|---|---|---|
| Gly 161 | - | expression tag |
| Ser 162 | - | expression tag |
| His 163 | - | expression tag |
| Met 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 54725.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1043.6 | |
| All* | Total formula weight | 55769.2 |
