4NCA

Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Argonaute	polymer	685	76728.7	2	UniProt (Q746M7) Pfam (PF22472) Pfam (PF18309) Pfam (PF22474)	Thermus thermophilus
2	C, E (C, E)	5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'	polymer	21	6588.3	2
3	D, F (D, F)	5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'	polymer	10	2980.0	2
4	G, H (G, H)	5'-D(*AP*CP*AP*AP*CP*C)-3'	polymer	6	1762.2	2
5	I, K (A, B)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	2	Chemie (TMP)
6	J, L, M, N, O... (A, B, C, D, E)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
7	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	320	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	176118.4
Non-Polymers*	Number of molecules	8
	Total formula weight	790.2
All*	Total formula weight	176908.6

*Water molecules are not included.