4NCA

Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Argonaute	polymer	685	76728.7	2	UniProt (Q746M7)	Thermus thermophilus
2	C, E (C, E)	5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'	polymer	21	6588.3	2
3	D, F (D, F)	5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'	polymer	10	2980.0	2
4	G, H (G, H)	5'-D(*AP*CP*AP*AP*CP*C)-3'	polymer	6	1762.2	2
5	I, K (A, B)	THYMIDINE-5'-PHOSPHATE	non-polymer		322.2	2	Chemie (TMP) PubChem (18531120) PubChem (20711568) PubChem (1139) PubChem (23657880) PubChem (24802545) PubChem (444919) PubChem (44361457) PubChem (25113134) PubChem (51397487) PubChem (5748250) PubChem (9700) PubChem (10147784) PubChem (5274091) PubChem (129069890) PubChem (133126478) PubChem (164603144)
6	J, L, M, N, O... (A, B, C, D, E)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG) PubChem (888)
7	Q, R, S, T, U... (A, B, C, D, E...)	water	water		18.0	320	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	176118.4
Non-Polymers*	Number of molecules	8
	Total formula weight	790.2
All*	Total formula weight	176908.6

*Water molecules are not included.