4N9F
Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | U, C, I, O, V... | Cullin-5 | polymer | 311 | 36386.8 | 12 | UniProt (Q93034) Pfam (PF00888) In PDB | Homo sapiens (human) | CUL-5, Vasopressin-activated calcium-mobilizing receptor 1, VACM-1 |
2 | Y, E, K, Q, Z... | Transcription elongation factor B polypeptide 1 | polymer | 96 | 10843.4 | 12 | UniProt (Q15369) Pfam (PF03931) In PDB | Homo sapiens (human) | Elongin 15 kDa subunit, Elongin-C, EloC, RNA polymerase II transcription factor SIII subunit C, SIII p15 |
3 | X, D, J, P, W... | Transcription elongation factor B polypeptide 2 | polymer | 102 | 11488.0 | 12 | UniProt (Q15370) Pfam (PF00240) In PDB | Homo sapiens (human) | Elongin 18 kDa subunit, Elongin-B, EloB, RNA polymerase II transcription factor SIII subunit B, SIII p18 |
4 | a, F, L, R, c... | Core-binding factor subunit beta | polymer | 170 | 20272.6 | 12 | UniProt (Q13951) Pfam (PF02312) In PDB | Homo sapiens (human) | CBF-beta, Polyomavirus enhancer-binding protein 2 beta subunit, PEA2-beta, PEBP2-beta, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor beta subunit |
5 | b, G, M, S, d... | Virion infectivity factor | polymer | 176 | 20982.2 | 12 | UniProt (Q72499) Pfam (PF00559) UniProt (by SIFTS) (P12504) In PDB | Human immunodeficiency virus 1 | |
6 | b, G, M, S, d... | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) |
Sequence modifications
U, C, I, O, V, f, l, r, x, 3, 9, w: 12 - 321 (UniProt: Q93034)
PDB | External Database | Details |
---|---|---|
Ala 11 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 60 |
Total formula weight | 1199677.0 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 784.9 | |
All* | Total formula weight | 1200461.9 |