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4N76

Structure of Thermus thermophilus Argonaute bound to guide DNA and cleaved target DNA with Mn2+

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Argonautepolymer68576728.72UniProt (Q746M7)
Pfam (PF22472)
Pfam (PF18309)
Pfam (PF22474)
Thermus thermophilus
2C, D
(C, E)
5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3'polymer216588.32
3E, F
(D, F)
5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'polymer102980.02
4G, H, I, K
(B, C)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
5J
(B)
THYMIDINE-5'-PHOSPHATEnon-polymer322.21Chemie (TMP)
6L, M, N, O, P
(A, B, C, E, F)
waterwater18.027Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight172593.9
Non-Polymers*Number of molecules5
Total formula weight542.0
All*Total formula weight173135.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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