4N5T
The 1.7A Crystal Structure of MDMX with a Stapled Peptide, ATSP-7041
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Protein Mdm4 | polymer | 90 | 10322.1 | 1 | UniProt (Q7ZUW7) Pfam (PF02201) In PDB | Danio rerio (leopard danio zebra danio zebra fish) | Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4 |
| 2 | B | ATSP-7041 stapled-peptide | polymer | 15 | 1734.0 | 1 | BIRD (PRD_001189) | synthetic construct | |
| 3 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 17 - 106 (UniProt: Q7ZUW7)
| PDB | External Database | Details |
|---|---|---|
| Val 46 | Leu 46 | engineered mutation |
| Leu 95 | Val 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 12056.1 | |
| All* | Total formula weight | 12056.1 |
